“Statin users switch to anaerobic metabolism sooner during maximal exercise performance, are more prone to muscle fatigability during repeated muscle contractions, and have a reduced mitochondrial oxidative capacity of the muscle than nonstatin users”

[ctct form=”741″]Evidence for Disturbances in Energy Metabolism

Neeltje A. E. Allard; Tom J. J. Schirris; Rebecca J. Verheggen; Frans G. M. Russel; Richard J. Rodenburg; Jan A. M. Smeitink; Paul D. Thompson; Maria T. E. Hopman; Silvie Timmers J Clin Endocrinol Metab. 2018;103(1):75-84.

Ok, now, stratify risk increase by level of lost exercise compared to same individuals benefit of taking a statin – any of the Emergency Medicine Sports Med interested folks want to ask for subject level data and knock out a quick quantitative model?

full paper here

medscape summary here

 

 

SaveSave

Author: Jason Wilson, MD

Jason W. Wilson, MD, MA, FACEP is an emergency medicine physician at Tampa General Hospital. He serves as a core faculty member and Associate Professor in the Division of Emergency Medicine, Department of Internal Medicine at the Morsani College of Medicine at the University of South Florida. He also holds an affiliated faculty appointment with the Department of Anthropology at the University of South Florida. Dr. Wilson serves as the Medical Director for the Clinical Decision Unit at Tampa General Hospital as well as the Associate Medical Director for the Adult ED. In addition, Dr. Wilson is the research director for the emergency medicine residency program.

Leave a Reply

Your email address will not be published.